Key result
Circadian variations demonstrate a significant peak in the incidence of acute myocardial infarction during the morning waking hours.
This review highlights the clinical implications of circadian variations in cardiovascular events, particularly the morning peak in acute myocardial infarction.
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Supports morning chronotherapy consideration in AMI prevention; confirms established peak but leaves prospective trials needed.
Mulcahy et al. (1991) conducted a review in Cardiovascular disease. Morning waking hours (circadian variations) was evaluated on Incidence of acute myocardial infarction. Circadian variations demonstrate a significant peak in the incidence of acute myocardial infarction during the morning waking hours.
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