Why the study?
Does Cryolife O'Brien stentless bioprosthesis implantation provide satisfactory clinical and hemodynamic outcomes in elderly patients requiring aortic valve replacement?
Does Cryolife O'Brien stentless bioprosthesis implantation provide satisfactory clinical and hemodynamic outcomes in elderly patients requiring aortic valve replacement?
The Cryolife O'Brien stentless bioprosthesis provides excellent long-term survival and favorable hemodynamic improvements in elderly patients undergoing aortic valve replacement.
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Supports favorable 7-year outcomes with this stentless valve in elderly AVR; leaves open randomized comparisons to stented bioprostheses.
OBJECTIVE: Seven-year clinical and hemodynamic results of the Cryolife O'Brien (CLOB) stentless bioprosthesis in elderly patients are reported. METHODS: From 1993 to 2000, 36 patients aged >75 years had a CLOB implanted in the aortic position. Eighteen (50%) were male. All patients were monitored with serial echocardiograms performed preoperatively, at discharge, six months, one year and yearly thereafter. RESULTS: The 30-day mortality was 2.4% (1/36). Actuarial survival at one, five and seven years were 96.7+/-1.5, 94.8+/-2.0 and 94.8+/-2.0%, respectively. Peak and mean gradients (PG and MG) reduced and effective orifice area index (EOAI) increased over time (P<0.001). Left ventricular mass index (LVMI) reduced by 32 g/m2 at discharge (P<0.001) and by 33 g/m2 at six months (P<0.001) without further significant changes. CONCLUSIONS: In our series CLOB xenograft resulted to be a satisfactory valve substitute in elderly patients.
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Sandro Gelsomino (2002) studied this question.
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