Key result
The stented Labcor Dokimos Plus and stentless Sorin Freedom Solo pericardial bioprostheses demonstrated comparable hemodynamic performance at discharge, with no significant differences in effective orifice areas or mean pressure gradients.
Why the study?
Does a contemporary stented pericardial bioprosthesis provide comparable hemodynamic performance to a stentless bioprosthesis in patients undergoing aortic valve replacement?
Cohort (n=114)
No
Does a contemporary stented pericardial bioprosthesis provide comparable hemodynamic performance to a stentless bioprosthesis in patients undergoing aortic valve replacement?
Contemporary stented pericardial bioprostheses offer comparable early hemodynamic performance to stentless valves, suggesting the stent does not significantly obstruct effective blood flow in larger valve sizes.
Supports stented bioprostheses without early hemodynamic penalty in AVR; leaves open durability and outcome comparisons versus stentless valves.
PURPOSE: Hemodynamic performance of aortic valve bioprostheses is essential for reliable function and durability. So far, the supra-annularly implanted stentless Sorin Freedom Solo (SFS) demonstrated unsurpassed hemodynamic properties. As contemporary stented and externally mounted pericardial bioprostheses, like the Labcor Dokimos Plus (LDP), also improve hemodynamic performance, these types of valves were compared in this study. METHODS: A total of 218 patients, who underwent aortic valve replacement with the LDP or the SFS, were matched retrospectively 1:1 on variables affecting hemodynamic measurements: implanted valve size, age, sex, and body surface area (BSA). With matching tolerance for valve size and gender of 0%, for age and BSA of 5%, 57 patient-pairs were yielded. Operative data, clinical, and hemodynamic outcome were analyzed. CONCLUSION: Contemporary stented and stentless pericardial bioprostheses showed excellent hemodynamic properties without significant differences in EOAs and indexed EOAs.
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Christ et al. (2017) conducted a cohort in Aortic valve replacement (n=114). Labcor Dokimos Plus (LDP) stented bioprosthesis vs. Sorin Freedom Solo (SFS) stentless bioprosthesis was evaluated on Hemodynamic performance (mean pressure gradients, effective orifice area, and indexed effective orifice area). The stented Labcor Dokimos Plus and stentless Sorin Freedom Solo pericardial bioprostheses demonstrated comparable hemodynamic performance at discharge, with no significant differences in effective orifice areas or mean pressure gradients.
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