Key result
Biological aortic valve replacement carries a long-term mortality rate of ~4.8 per 100 person-years.
Why the study?
A comprehensive and contemporary overview of the long-term safety outcomes after aortic valve replacement with conventional biological heart valves was needed.
Meta-Analysis (n=29,608)
Conventional biological aortic valve replacement is associated with an all-cause mortality of 6.33/100 patient-years and major long-term complications including thromboembolism, PPM implantation, reoperation, stroke, and SVD.
Answers are grounded in this paper and cite their sources.
Informs prognosis and shared decisions for biological AVR candidates; provides pooled reference for future comparative studies.
OBJECTIVE: To provide a comprehensive and contemporary overview of the long-term safety outcomes after aortic valve replacements (AVR) with conventional biological heart valve (stented or stentless). METHODS: ., patients with renal failure, or pregnancy), without the report of biological valve type, or with study population size less than 100. The meta-analysis was performed using Stata 14.0 software. RESULTS: : 0.36-0.58). CONCLUSION: The all-cause mortality for conventional biological AVR was 6.33/100 patient-years. Thromboembolism, PPM implantation, reoperation, stroke, and SVD were major long term complications.
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A 2020 study conducted a meta-analysis in Aortic valve disease requiring replacement (n=29,608). Biological valves was evaluated on All-cause mortality (4.77 per 100 person-years). In patients undergoing aortic valve replacement, the long-term all-cause mortality rate for biological valves was 4.77 per 100 person-years.
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