Key result
Intravenous administration of either 5% dextrose in water or 20% mannitol resulted in 0 cases of postoperative anuria among 27 patients, compared to 5 cases among 28 patients receiving no free fluid.
Why the study?
Does intravenous mannitol or water load prevent postoperative anuria and improve urinary output in patients undergoing surgery for abdominal aortic aneurysms or aorto-iliac occlusive disease?
Cohort (n=55)
No
Does intravenous mannitol or water load prevent postoperative anuria and improve urinary output in patients undergoing surgery for abdominal aortic aneurysms or aorto-iliac occlusive disease?
Absolute Event Rate: 0% vs 17.9%
Intravenous mannitol or water load during abdominal aortic surgery prevents postoperative anuria and improves urinary output compared to fluid restriction.
No takes yet. Share an insight, caveat, or question.
May support mannitol or dextrose to avert anuria after aortic surgery; leaves open need for randomized confirmation.
BAIRD et al. (1963) conducted a cohort in Abdominal aortic aneurysm and aorto-iliac occlusive disease (n=55). Intravenous mannitol or 5% dextrose in water vs. No free fluid (blood replacement only) was evaluated on Postoperative anuria / acute renal failure. Intravenous administration of either 5% dextrose in water or 20% mannitol resulted in 0 cases of postoperative anuria among 27 patients, compared to 5 cases among 28 patients receiving no free fluid.
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