Key result
Total resection followed by chemotherapy and radiotherapy failed to halt the spread of left atrial myxofibrosarcoma, resulting in tumor recurrence at 14 months and death from brain metastasis.
Case Report (n=1)
Cardiac myxofibrosarcoma is a rare, highly malignant tumor for which adjuvant chemotherapy and radiotherapy may be ineffective.
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Adjuvant chemoradiotherapy after resection may fail to prevent recurrence or metastasis in left atrial myxofibrosarcoma; leaves open need for novel therapies in this rare malignancy.
Yi et al. (1996) conducted a case report in Primary left atrial myxofibrosarcoma (n=1). Total resection, chemotherapy, and local irradiation was evaluated on Tumor recurrence and survival. Total resection followed by chemotherapy and radiotherapy failed to halt the spread of left atrial myxofibrosarcoma, resulting in tumor recurrence at 14 months and death from brain metastasis.
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