Key result
Surgical resection and chemotherapy for a primary left atrial myxofibrosarcoma were followed by tumor recurrence and patient death 3 months post-surgery.
Case Report (n=1)
Primary myxofibrosarcoma of the left atrium is a highly aggressive tumor with a poor prognosis despite surgical resection and chemotherapy.
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Portends poor survival in left atrial myxofibrosarcoma despite resection and chemotherapy; leaves open optimal management for this rare tumor.
A 63-year-old woman with progressive dyspnea underwent transthoracic echocardiography and was found to have a large multilobed mass in the left atrium that was attached to lateral wall. On inspection during surgery, the tumor was found to infiltrate the posterior mitral annulus and leaflet. The patient underwent surgical resection of the tumor and mitral valve replacement. Histologic and cytochemical evaluation confirmed that the tumor was a myxofibrosarcoma. Despite chemotherapy, the tumor recurred and the patient died 3 months after surgery.
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Lazaros et al. (2008) conducted a case report in Primary Myxofibrosarcoma of the Left Atrium (n=1). Surgical resection, mitral valve replacement, and chemotherapy was evaluated on Tumor recurrence and survival. Surgical resection and chemotherapy for a primary left atrial myxofibrosarcoma were followed by tumor recurrence and patient death 3 months post-surgery.
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