Key result
Treatment with a myocutaneous flap combined with vancomycin-loaded calcium sulphate achieved satisfactory results, including complete wound and bone healing, in 100% of 14 patients with chronic osteomyelitis.
Why the study?
Does vancomycin-loaded calcium sulphate combined with surgical debridement and myocutaneous flap improve healing in patients with chronic osteomyelitis?
Population
14 patients with chronic osteomyelitis of the tibia, calcaneus, or ankle, average age 47 years, 12 males and…
Design
Case_series
Follow-up
two years and two months
Authors
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May warrant consideration in refractory cases; leaves open need for randomized trials to confirm efficacy.
Case Report (n=14)
Does vancomycin-loaded calcium sulphate combined with surgical debridement and myocutaneous flap improve healing in patients with chronic osteomyelitis?
Vancomycin-loaded calcium sulphate combined with a myocutaneous flap and surgical debridement is an effective treatment for chronic osteomyelitis of the tibia and calcaneus.
Shen et al. (2014) conducted a case report in chronic osteomyelitis (n=14). Vancomycin-loaded calcium sulphate combined with surgical debridement, myocutaneous flap, and systemic antibiotics was evaluated on Satisfactory results (no growth on cultures, wound healing, and bone healing). Treatment with a myocutaneous flap combined with vancomycin-loaded calcium sulphate achieved satisfactory results, including complete wound and bone healing, in 100% of 14 patients with chronic osteomyelitis.
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