This is the authors' abstract. We don't add key points for this paper.
Investigating the interplay between cytochrome-P450 and its redox partners (CPR and cytochrome-b5) is vital for understanding the metabolism of most hydrophobic drugs. Dynamic structural interactions with the ternary complex, with and without substrates, captured by NMR reveal a gating mechanism for redox partners to promote P450 function.
Answers are grounded in this paper and cite their sources.
No takes yet. Share an insight, caveat, or question.
Gentry et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: