Key result
Ischaemic myocardial tissue lost an average of 26% of 15-micrometer preocclusion microspheres over 10 hours compared with nonischaemic tissue, migrating mostly through venous pathways.
Microspheres migrate from infarcted myocardium over time, limiting their utility for measuring tissue blood flow in prolonged coronary occlusion models.
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Microsphere migration from ischaemic tissue may limit flow quantification accuracy in prolonged-occlusion animal models; leaves open microsphere reliability for infarct perfusion studies.
LEKVEN et al. (1980) studied Infarcted myocardium. 15 micrometer microspheres vs. Nonischaemic tissue was evaluated on Loss of preocclusion spheres. Ischaemic myocardial tissue lost an average of 26% of 15-micrometer preocclusion microspheres over 10 hours compared with nonischaemic tissue, migrating mostly through venous pathways.
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