Key result
Early dysautonomia following mild traumatic brain injury was significantly correlated with late depression at 18 months in female patients (ρ = -0.411; p < 0.05).
Why the study?
Does early dysautonomia detected by heart rate variability predict late depression in female patients following mild traumatic brain injury?
Cohort (n=264)
Does early dysautonomia detected by heart rate variability predict late depression in female patients following mild traumatic brain injury?
Effect estimate: ρ = -0.411
p-value: p=< .05
Early dysautonomia detected by heart rate variability in the first week following mild traumatic brain injury predicts late depression in female patients.
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Hypothesis-generating association in women post-mTBI; does not support practice change and requires prospective validation.
Sung et al. (2015) conducted a cohort in Mild traumatic brain injury (mTBI) (n=264). Early dysautonomia (reduced heart rate variability) vs. Healthy controls / normal heart rate variability was evaluated on Late depression at 18 months (Beck Depression Inventory scores) (ρ = -0.411, p=< .05). Early dysautonomia following mild traumatic brain injury was significantly correlated with late depression at 18 months in female patients (ρ = -0.411; p < 0.05).
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