Population
Isolated working rat hearts
Comparison
Exposure to different concentrations of… vs Different concentrations of fatty acids
Design
Preclinical
Authors
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Substrate supply may primarily regulate myocardial fatty acid oxidation independent of ACC/AMPK; leaves open translation to human cardiac metabolism.
Myocardial substrate supply primarily regulates fatty acid oxidation rates under nonstressful physiological conditions, independent of ACC and AMPK activities.
Longnus et al. (2001) studied this question.
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