Population
Cardiac muscle cells (aerobic heart)
Design
Review
Authors
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Challenges malonyl-CoA primacy in cardiac FAO; leaves open mechanisms linking energy demand to oxidation and therapeutic targets.
This review proposes that malonyl-CoA acts as a feedback regulator of fatty acid import in response to cardiac energy demands, rather than a master on-off switch.
Saks et al. (2006) studied this question.
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