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A comprehensive review with 337 references for the analysis of some selected 4-quinolone drugs belonging to the first and second generations since 2006 up till now is presented. This group includes nalidixic acid, oxolinic acid, piromidic acid, pipemidic acid and rosoxacin from the first generation and enoxacin, fleroxacin, nadifloxacin, pefloxacin and rufloxacin from the second generation. The review covers most of the methods described for the analysis of these drugs, either per se , in dosage forms, biological fluids, environmental samples, cosmetics, animal tissues and feed-premix samples.
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Belal et al. (2017) studied this question.
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