Association between Mean Ocular Perfusion Pressure and Diabetic Retinopathy in a Northeastern Chinese Population.

This is the authors' abstract. We don't add key points for this paper.

OBJECTIVE: To evaluate the association between diabetic retinopathy (DR) and mean ocular perfusion pressure (MOPP) in patients with type 2 diabetes mellitus (T2DM). METHODS: Patients from the Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT), a community-based prospective cohort study conducted in northeast China, were included in this study. The presence and severity of DR were determined by grading fundus photographs according to the Early Treatment Diabetic Retinopathy Study (ETDRS) retinopathy scale. Systolic and diastolic blood pressure (SBP and DBP) were recorded using an electronic sphygmomanometer. Intraocular pressure (IOP) was measured using an iCare rebound tonometer. MOPP was calculated using the formula MOPP = 2/3 [DBP + 1/3 (SBP - DBP)] - IOP. RESULTS: : 1.01-1.04). CONCLUSIONS: The results suggest that increased MOPP was associated with DR and macular edema in northeastern Chinese patients with T2DM.