Key result
Cardiac resynchronization therapy yielded an echo response rate of 57%, and responders had significantly more baseline dyssynchrony compared to nonresponders (P < .05).
Why the study?
Does cardiac resynchronization therapy improve multi-plane mechanical dyssynchrony and predict reverse remodeling in heart failure patients?
Observational (n=70)
Does cardiac resynchronization therapy improve multi-plane mechanical dyssynchrony and predict reverse remodeling in heart failure patients?
Combining radial and longitudinal dyssynchrony measures on echocardiography modestly predicts reverse remodeling following cardiac resynchronization therapy.
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Baseline dyssynchrony may predict CRT response; hypothesis-generating for multi-plane echo measures in heart failure.
Kaufman et al. (2009) conducted an observational in Heart failure (n=70). Cardiac resynchronization therapy vs. Baseline (pre-CRT) / Nonresponders was evaluated on CRT echo response (≥ 15% decrease in left ventricular end-systolic volume). Cardiac resynchronization therapy yielded an echo response rate of 57%, and responders had significantly more baseline dyssynchrony compared to nonresponders (P < .05).
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