Why the study?
Does stress 99mTc-MIBI gated SPECT predict future cardiac events in asymptomatic patients undergoing hemodialysis?
Population
31 asymptomatic patients undergoing hemodialysis (20 men, 11 women), mean age 45 years (range, 25-75 years).
Design
Cohort
Follow-up
median 20 months (range, 14-28 months)
Key result
Abnormal 99mTc-MIBI gated myocardial perfusion scintigraphy was associated with a significantly higher rate of cardiac events compared to normal scans (78% vs 9%, P<0.0001).
Authors
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May support risk stratification in asymptomatic hemodialysis; leaves open whether gated SPECT improves outcomes over standard care.
Cohort (n=31)
Does stress 99mTc-MIBI gated SPECT predict future cardiac events in asymptomatic patients undergoing hemodialysis?
Absolute Event Rate: 78% vs 9%
p-value: p=<0.0001
In asymptomatic hemodialysis patients, abnormal 99mTc-MIBI gated SPECT is strongly associated with future cardiac events and correlates with markers of inflammation.
Çağlar et al. (2005) conducted a cohort in Asymptomatic patients undergoing hemodialysis (n=31). Abnormal 99mTc-MIBI gated myocardial perfusion scintigraphy vs. Normal myocardial perfusion scintigraphy was evaluated on Cardiac event (p=<0.0001). Abnormal 99mTc-MIBI gated myocardial perfusion scintigraphy was associated with a significantly higher rate of cardiac events compared to normal scans (78% vs 9%, P<0.0001).
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