Key result
Nonsurgical periodontal therapy significantly reduced total cholesterol, LDL, VLDL, and triglycerides, and increased HDL at 3 months in patients with chronic periodontitis.
Why the study?
Does nonsurgical periodontal therapy improve serum lipid levels in patients with chronic periodontitis?
Cohort (n=50)
Does nonsurgical periodontal therapy improve serum lipid levels in patients with chronic periodontitis?
Nonsurgical periodontal therapy in patients with chronic periodontitis significantly improves serum lipid profiles, suggesting a link between periodontal health and cardiovascular risk factors.
May support integrating periodontal care into CV risk management; leaves open confirmation via RCTs.
Aim: There is growing evidence that periodontitis may affect general health. This study was assigned to explore changes in cholesterol levels following nonsurgical periodontal therapy in patients with chronic periodontitis. Materials and methods: Periodontal parameters and lipid profile (total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides and very low-density lipoprotein) were evaluated in 50 subjects suffering from moderate to severe generalized chronic periodontitis. Results: At third month, there was significant reduction in total cholesterol, low density lipoprotein, very low density lipoprotein, triglyceride and increase in high density lipoprotein after nonsurgical periodontal therapy (NSPT). Also, the reduction in bleeding on probing, pocket depth and attachment level were statistically significant in the treatment group. Conclusion: The results of our study showed that periodontal destruction and serum lipid levels are positively correlated and nonsurgical periodontal treatment in chronic periodontitis patients resulted in significant changes in the concentration of total cholesterol, triglycerides, HDL. LDL levels in blood serum.
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Thombre et al. (2011) conducted a cohort in Moderate to severe generalized chronic periodontitis (n=50). Nonsurgical periodontal therapy vs. Baseline was evaluated on Changes in lipid profile (total cholesterol, HDL, LDL, triglycerides, VLDL). Nonsurgical periodontal therapy significantly reduced total cholesterol, LDL, VLDL, and triglycerides, and increased HDL at 3 months in patients with chronic periodontitis.
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