Key result
Every hour increase in time from ED triage to appendectomy incision was independently associated with a 2% increase in the odds of appendiceal perforation (OR 1.02; 95% CI 1.00-1.04; P=0.03).
Why the study?
Does increased time from ED triage to appendectomy increase the risk of appendiceal perforation in children with nonperforated appendicitis?
Population
857 children younger than 18 years hospitalized with appendicitis, who had a computed tomography scan…
Comparison
Increased time from emergency department triage… vs Shorter time from ED triage to appendectomy
Design
Cohort
Authors
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May support expedited appendectomy in children; hypothesis-generating for prospective timing trials.
Cohort (n=857)
Yes
Does increased time from ED triage to appendectomy increase the risk of appendiceal perforation in children with nonperforated appendicitis?
Odds Ratio: 1.02 (95% CI 1–1.04)
p-value: p=0.03
Prolonged delays from ED triage to appendectomy in children with nonperforated appendicitis are associated with a small but significant increased risk of perforation.
Meltzer et al. (2016) conducted a cohort in appendicitis (n=857). Time from ED triage to appendectomy incision was evaluated on Appendiceal perforation as documented in the surgical report (OR 1.02, 95% CI 1.00-1.04, p=0.03). Every hour increase in time from ED triage to appendectomy incision was independently associated with a 2% increase in the odds of appendiceal perforation (OR 1.02; 95% CI 1.00-1.04; P=0.03).
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