Key result
High cardiorespiratory fitness was associated with lower odds of having carotid atherosclerosis compared to low cardiorespiratory fitness in men with type 2 diabetes.
Why the study?
Is higher cardiorespiratory fitness associated with lower carotid artery intima media thickness in men with type 2 diabetes?
Cross-Sectional (n=746)
No
Is higher cardiorespiratory fitness associated with lower carotid artery intima media thickness in men with type 2 diabetes?
Higher cardiorespiratory fitness is inversely associated with carotid atherosclerosis in men with type 2 diabetes, highlighting the potential vascular benefits of fitness in this population.
Answers are grounded in this paper and cite their sources.
Does not yet support practice change in T2D men; hypothesis-generating for fitness benefits on carotid atherosclerosis.
BACKGROUND: We tested the hypothesis that higher levels of cardiorespiratory fitness are inversely associated with carotid artery intima media thickness in 746 (age 53 ± 7 yrs) men with type 2 diabetes. METHODS: We measured common carotid intima media thickness and defined carotid atherosclerosis as a carotid intima media thickness > 1.0 mm. Cardiorespiratory fitness was directly measured by peak oxygen uptake using expired gases analysis during a standard treadmill test. RESULTS: Cardiorespiratory fitness was independently associated with common carotid intima media thickness in multivariable regression (β = -0.15, P < .05). After adjusting for established risk factors, high and moderate cardiorespiratory fitness were associated with lower odds ratios for having carotid atherosclerosis--0.49 (95% CI, 0.30-0.81), and 0.59 (95% CI, 0.38-0.92), respectively--as compared with low cardiorespiratory fitness. Each 1 metabolic equivalent increment higher cardiorespiratory fitness was associated with 27% (OR = 0.73; 95% CI, 0.61-0.87) lower prevalence of carotid atherosclerosis. CONCLUSIONS: These results suggest that high cardiorespiratory fitness is inversely associated with common carotid intima media thickness in men with type 2 diabetes.
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Jae et al. (2012) conducted a cross-sectional in Type 2 diabetes (n=746). High cardiorespiratory fitness vs. Low cardiorespiratory fitness was evaluated on Carotid atherosclerosis (carotid intima media thickness > 1.0 mm) (OR 0.49, 95% CI 0.30-0.81, p=<0.001). High cardiorespiratory fitness was associated with lower odds of having carotid atherosclerosis compared to low cardiorespiratory fitness in men with type 2 diabetes.
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