Key result
Percutaneous closure with a nickel-containing Amplatzer PFO occluder in a 38-year-old man resulted in pericarditis, atrial fibrillation, and increased migraines due to nickel hypersensitivity.
Case Report (n=1)
Nickel hypersensitivity from Amplatzer PFO occluders should be considered as a potential etiology for post-procedural pericarditis and atrial fibrillation.
Nickel hypersensitivity may underlie post-PFO occluder complications; this case leaves open whether nickel-free devices reduce risk.
A 38-year-old man with a history of migraine headaches with aura and one episode of ischemic stroke was found to have a patent foramen ovale (PFO). After percutaneous closure with the nickel-containing Amplatzer PFO occluder, the patient developed pericarditis, atrial fibrillation, and increased migraine headaches with aura that abated with oral prednisone. He tested positive for nickel hypersensitivity, which we conclude is the likely etiology of his pericarditis.
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Lai et al. (2005) conducted a case report in Patent foramen ovale (n=1). Amplatzer PFO occluder was evaluated on Development of pericarditis, atrial fibrillation, and increased migraine headaches. Percutaneous closure with a nickel-containing Amplatzer PFO occluder in a 38-year-old man resulted in pericarditis, atrial fibrillation, and increased migraines due to nickel hypersensitivity.
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