Key result
In rabbit atrial muscle, action potentials elicited after a long period of rest (>30 seconds) lacked a plateau phase and exhibited a prominent after-depolarization.
The prolonged action potential plateau of a periodically excited heart may result from the long-lasting small after-depolarization following each preceding action potential.
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May explain plateau maintenance during periodic atrial excitation; leaves open relevance to human electrophysiology.
Tanaka et al. (1967) studied this question. Prolonged periods of rest prior to electrical stimulation vs. Shorter intervals of excitation was evaluated on Configuration of the action potential (duration and plateau phase). In rabbit atrial muscle, action potentials elicited after a long period of rest (>30 seconds) lacked a plateau phase and exhibited a prominent after-depolarization.
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