Key result
Three lots of human immune serum globulin contained neutralizing antibodies to coxsackieviruses B3 and B4 (titers 400 to ≥2000) and coxsackievirus A9 and ECHO viruses 5 and 9 (titers 100 to 400).
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May support passive immunization against enteroviruses; leaves open clinical efficacy trials.
Dagan et al. (1983) studied this question. Human immune serum globulin was evaluated on Neutralizing antibody titers to selected non-polio enteroviruses. Three lots of human immune serum globulin contained neutralizing antibodies to coxsackieviruses B3 and B4 (titers 400 to ≥2000) and coxsackievirus A9 and ECHO viruses 5 and 9 (titers 100 to 400).
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