Key result
Rectally administered thiopentone provided a 93.3% success rate for completing CT scans in children under 5 years of age, compared to a 100% success rate with general anaesthesia.
Why the study?
Does intrarectal thiopentone sodium provide safe and effective sedation compared to general anaesthesia in pediatric patients undergoing computerized tomography?
Population
60 children below 5 years of age undergoing computerized tomography
Comparison
Thiopentone sodium administered rectally vs General anaesthesia with a uniform technique
Design
Cohort
Authors
Loading...
Should not yet change sedation practice for pediatric CT; hypothesis-generating and requires randomized trials versus general anaesthesia.
RCT (n=60)
Open-label
Randomly assigned
No
Does intrarectal thiopentone sodium provide safe and effective sedation compared to general anaesthesia in pediatric patients undergoing computerized tomography?
Absolute Event Rate: 93.3% vs 100%
Intrarectal thiopentone is a safe and effective alternative to general anaesthesia for sedating pediatric patients undergoing CT scans, though general anaesthesia has a higher success rate.
Hafiz et al. (2007) conducted an RCT in Computerized axial tomography in children (n=60). Rectal thiopentone sodium vs. General anaesthesia was evaluated on Success rate of completing the CT scan. Rectally administered thiopentone provided a 93.3% success rate for completing CT scans in children under 5 years of age, compared to a 100% success rate with general anaesthesia.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: