Key result
Preemptive alcohol septal ablation before valve-in-valve transcatheter mitral valve replacement was used to minimize acute LVOT obstruction risk during bioprosthetic valve fracture.
Why the study?
Preemptive alcohol septal ablation was evaluated to minimize the risk of acute left ventricular outflow tract obstruction before transcatheter mitral valve replacement with bioprosthetic valve fracture.
Preemptive alcohol septal ablation may be a viable strategy to prevent acute left ventricular outflow tract obstruction in high-risk patients undergoing valve-in-valve TMVR with bioprosthetic balloon fracture.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for preemptive septal ablation in high-risk TMVR; prospective trials needed before clinical adoption.
A 78-year-old woman with bioprosthetic mitral valve degeneration at high risk for reoperation was referred for transcatheter mitral valve replacement. We describe the use of a preemptive alcohol septal ablation pre-procedurally to minimize the risk of acute left ventricular outflow tract obstruction given the anticipated need for a bioprosthetic valve fracture. (Level of Difficulty: Advanced.)
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Gonzalez et al. (2021) studied this question. Preemptive alcohol septal ablation before valve-in-valve transcatheter mitral valve replacement was used to minimize acute LVOT obstruction risk during bioprosthetic valve fracture.
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