Key result
Compared to nonpregnant women, pregnancy was associated with similar ischemic stroke risk, higher hemorrhagic stroke risk (IRR 1.4), and an 8-fold higher risk of CVT (IRR 8.1; 95% CI 6.5-10.1).
Why the study?
Despite the potentially devastating effects of pregnancy-related stroke, few studies have examined its incidence by type of stroke.
Does pregnancy increase the incidence of stroke compared to nonpregnant women?
Population
6,297,698 women aged 15-49 years who gave birth in France without prior stroke
Comparison
Pregnant vs nonpregnant women
Design
Nationwide database study
Follow-up
First 6 weeks of postpartum
Authors
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May warrant heightened peripartum vigilance for CVT and rising IS/HS; extends prior incidence data by type and trends in a large national cohort.
Cohort (n=6,297,698)
Yes
Does pregnancy increase the incidence of stroke compared to nonpregnant women?
Relative Risk: 8.1 (95% CI 6.5–10.1)
Pregnancy is associated with a more than 8-fold higher risk of cerebral venous thrombosis and a slightly higher risk of hemorrhagic stroke compared to nonpregnant women, with incidence rates rising over time.
Gabet et al. (2022) conducted a cohort in Pregnancy-related stroke (n=6,297,698). Pregnancy vs. Nonpregnant women was evaluated on Cerebral venous thrombosis (CVT) (IRR 8.1, 95% CI 6.5-10.1). Compared to nonpregnant women, pregnancy was associated with similar ischemic stroke risk, higher hemorrhagic stroke risk (IRR 1.4), and an 8-fold higher risk of CVT (IRR 8.1; 95% CI 6.5-10.1).
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