Key result
Having 6 or more pregnancies was associated with an increased age-adjusted risk for any stroke (RR 1.7; 95% CI 1.2-2.3), which attenuated after adjusting for stroke risk factors (RR 1.3).
Why the study?
Does a higher number of pregnancies increase the risk for stroke and stroke subtypes in women?
Population
3,852 women aged 45 to 74 years from the National Health and Nutrition Examination Survey Epidemiology…
Comparison
6 or more pregnancies (or history of pregnancy) vs Fewer pregnancies or nulligravida
Design
Cohort
Follow-up
20-year
Authors
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High multiparity should not yet alter stroke prevention; leaves open independent risk beyond traditional factors.
Cohort (n=3,852)
Yes
Does a higher number of pregnancies increase the risk for stroke and stroke subtypes in women?
Relative Risk: 1.7 (95% CI 1.2–2.3)
A high number of pregnancies (≥6) may be associated with an increased risk of stroke, particularly cerebral infarction, though this is partially mediated by traditional stroke risk factors.
Qureshi et al. (1997) reported a cohort. 6 or more pregnancies vs. Fewer pregnancies was evaluated on Stroke, cerebral infarction, and intracerebral hemorrhage (RR 1.7, 95% CI 1.2-2.3). Having 6 or more pregnancies was associated with an increased age-adjusted risk for any stroke (RR 1.7; 95% CI 1.2-2.3), which attenuated after adjusting for stroke risk factors (RR 1.3).
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