ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion

This is the authors' abstract. We don't add key points for this paper.

patients exhibit increased IL-17, SOCS2, and TGF-β pathways and a negative association with overall survival. This unveils ZEB1's dual role in AML, entwining pro-tumoral and immune regulatory capacities in AML blasts.