Key result
Numerical simulation using ANSYS showed good agreement with experimental μPIV flow data in 3D mili-scale channels representing simplified anatomical models of blood vessels with stenoses.
This work validates a numerical simulation approach against experimental data, enabling more realistic future hemodynamic studies focusing on atherosclerosis in mili-scale arteries.
Validates simulation against experimental data in simplified stenotic models; leaves open translation to in vivo atherosclerosis hemodynamics.
This study reports μPIV flow data analysis and their comparison with numerical results of the flow in 3D mili-scale channels developed for hemodynamic studies. The 3D mili-scale channels represent simplified anatomical models of blood vessels constructed in polidimethylsiloxane (PDMS) and produced by a sucrose casting method. The CFD package used to simulate the flow was ANSYS. Vessels with stenoses were chosen to the study: a straight channel and a channel bifurcating in two daughter channels. The results show a good agreement between the numerical and the experimental data. This work will allow a more realistic approach for future hemodynamic studies focusing on atherosclerosis in mili- scale arteries.
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Doutel et al. (2013) studied Hemodynamics / Atherosclerosis. Numerical simulation (ANSYS) and μPIV flow data analysis was evaluated on Agreement between numerical and experimental data. Numerical simulation using ANSYS showed good agreement with experimental μPIV flow data in 3D mili-scale channels representing simplified anatomical models of blood vessels with stenoses.
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