Key result
Juxtaaortic balloon counterpulsation significantly increased cardiac output (from 2.33 to 2.61 L/min, p<0.05) and provided hemodynamic improvement comparable to intraaortic counterpulsation in sheep.
Why the study?
Does juxtaaortic balloon counterpulsation improve hemodynamics compared to intraaortic balloon counterpulsation in an animal model of acute heart failure?
Population
Experimental animals (open chest sheep) during induced acute cardiac failure
Comparison
Juxtaaortic balloon counterpulsation achieved… vs Intraaortic balloon counterpulsation in…
Design
Preclinical
Authors
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Juxtaaortic counterpulsation merits human trials as a potential alternative; leaves open efficacy, safety, and advantages versus intraaortic devices.
Does juxtaaortic balloon counterpulsation improve hemodynamics compared to intraaortic balloon counterpulsation in an animal model of acute heart failure?
p-value: p=<0.05
In an open chest sheep model of acute heart failure, juxtaaortic balloon counterpulsation provides effective hemodynamic improvement comparable to standard intraaortic balloon counterpulsation.
Fischer et al. (2004) studied acute heart failure. Juxtaaortic balloon counterpulsation (JABC) vs. Intraaortic balloon counterpulsation (IABC) was evaluated on cardiac output (p=<0.05). Juxtaaortic balloon counterpulsation significantly increased cardiac output (from 2.33 to 2.61 L/min, p<0.05) and provided hemodynamic improvement comparable to intraaortic counterpulsation in sheep.
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