Effects of Intraaortic Balloon Counterpulsation on the Severity of Myocardial Ischemic Injury following Acute Coronary Occlusion
Why the study?
Does intraaortic balloon counterpulsation reduce myocardial ischemic injury following acute coronary occlusion?
Population
19 dogs following acute coronary occlusion and 2 patients with cardiogenic shock associated with acute…
Comparison
Intraaortic balloon counterpulsation (IABC) vs Control occlusion without IABC or baseline prior…
Design
Preclinical
Follow-up
Up to 3 hours post-occlusion
Authors
Discussion
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Implication
May reduce ischemic injury post-occlusion; leaves open confirmation in randomized human trials.
Structured PICO
Does intraaortic balloon counterpulsation reduce myocardial ischemic injury following acute coronary occlusion?
P
Population
19 dogs following acute coronary occlusion and 2 patients with cardiogenic shock associated with acute myocardial infarction
I
Intervention
Intraaortic balloon counterpulsation (IABC)
C
Comparator
Control occlusion without IABC or baseline prior to IABC
O
Outcome
Magnitude and severity of myocardial ischemic injury (measured by average S-T-segment elevation)surrogate
Intraaortic balloon counterpulsation effectively reduces the magnitude and extent of myocardial ischemic injury following acute coronary occlusion in both experimental models and patients with cardiogenic shock.
Cite This Study
Maroko et al. (1972) studied this question.