Key result
In a study of 38 subjects, multiple sclerosis was associated with significantly lower vagal power during natural and paced breathing compared to healthy controls.
Why the study?
Do patients with multiple sclerosis exhibit altered cardiac parasympathetic control as measured by vagal power compared to healthy controls?
Population
18 patients with multiple sclerosis and 20 healthy subjects matched with respect to age, education, and…
Design
Case-control
Authors
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May indicate parasympathetic dysfunction in MS; hypothesis-generating for autonomic monitoring in larger studies.
Case-Control (n=38)
Do patients with multiple sclerosis exhibit altered cardiac parasympathetic control as measured by vagal power compared to healthy controls?
Patients with multiple sclerosis exhibit reduced vagal power, indicating cardiac parasympathetic dysfunction that can be non-invasively assessed using heart rate variability.
Diamond et al. (1995) conducted a case-control in Multiple sclerosis (n=38). Multiple sclerosis vs. Healthy subjects was evaluated on Vagal power during natural and paced breathing. In a study of 38 subjects, multiple sclerosis was associated with significantly lower vagal power during natural and paced breathing compared to healthy controls.
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