Why the study?
Does multiple sclerosis cause impaired heart rate variability compared to healthy controls?
Population
34 patients with multiple sclerosis in a stable phase and 24 age and sex-matched healthy control subjects
Comparison
24-h electrocardiogram recording to assess heart… vs Healthy control subjects
Design
Case-control
Follow-up
24 hours
Authors
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May indicate autonomic dysregulation in MS; leaves open whether HRV predicts outcomes or warrants monitoring.
Does multiple sclerosis cause impaired heart rate variability compared to healthy controls?
Multiple sclerosis is associated with cardiovascular autonomic dysregulation, manifesting as impaired heart rate variability with increased sympathetic tone.
Monge-Argilés et al. (2009) studied this question.
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