Key result
Initial platelet count in patients with acute myocardial infarction undergoing primary PCI was not significantly associated with ST-segment improvement (P=0.275) or TIMI flow (P=0.380).
Why the study?
It remains unclear whether platelet count can predict outcomes, such as the degree of ST-segment depression and coronary flow rate, in patients with acute myocardial infarction undergoing PCI.
Does initial platelet count predict ST-segment improvement and coronary flow rate in patients with acute myocardial infarction undergoing primary PCI?
Observational (n=218)
No
Does initial platelet count predict ST-segment improvement and coronary flow rate in patients with acute myocardial infarction undergoing primary PCI?
p-value: p=0.275
Initial platelet count does not appear to predict angiographic or electrocardiographic outcomes in patients undergoing primary PCI for acute myocardial infarction.
Introduction: It is still unclear whether platelet count can predict the outcomes of acute myocardial infarction. In this study, we assessed the relationship between the initial platelet count on the degree of ST-segment depression and coronary flow rate among patients with MI who underwent percutaneous coronary intervention (PCI). Methods: In this study, a total of 218 patients suffering from MI, who underwent primary PCI during 2016-2017 (Seyed-Shohada hospital, Urmia, Iran) were selected by consensus method. Demographic information and past medical history such as diabetes mellitus (DM), cigarette smoking, using Integrilin, and door-to-balloon (DTB) time were recorded. All patients were investigated in terms of cell blood count. Serial electrocardiogram (ECG) was also performed and the degree of ST-segment elevation was measured. Results: The mean (SD) age of participants was 58.67 (11.44) years. The initial platelet count was similar between patients with and without improvement in the ST-segment (P = 0.275). There was no significant difference regarding thrombolysis in myocardial infarction (TIMI) between patients with and without improved ST-segment (P = 0.380). Conclusion: According to our results, the initial platelet count in patients who underwent angioplasty was not associated with coronary flow and echocardiographic responses to treatment.
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Afsargharehbagh et al. (2020) conducted an observational in Acute myocardial infarction (n=218). Initial platelet count was evaluated on Improvement in the ST-segment and coronary flow rate (TIMI) (p=0.275). Initial platelet count in patients with acute myocardial infarction undergoing primary PCI was not significantly associated with ST-segment improvement (P=0.275) or TIMI flow (P=0.380).
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