Key result
STEMI is linked to significantly higher platelet counts and activity indices compared to NSTEMI.
Why the study?
Platelet activation plays a crucial role in the atherothrombotic process underlying STEMI and NSTEMI, motivating this analysis of differences in platelet indices between STEMI and NSTEMI patients at Advent Hospital Bandar Lampung.
Observational (n=104)
No
Platelet count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), and Plateletcrit (PCT) are significantly higher in STEMI patients compared to NSTEMI patients, suggesting their potential utility as supplementary hematological markers in evaluating acute coronary syndrome.
Higher platelet counts associate with STEMI; hypothesis-generating for indices in MI differentiation, needing prospective validation before any clinical use.
Acute Coronary Syndrome (ACS) remains a major cause of cardiovascular morbidity and mortality worldwide. Platelet activation plays a crucial role in the atherothrombotic process underlying ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI). This study aimed to analyze differences in platelet indices between STEMI and NSTEMI patients at Advent Hospital Bandar Lampung. An analytical observational study with a retrospective approach was conducted involving 104 eligible patients. Data were collected from medical records and analyzed using the chi-square, Mann–Whitney, and independent samples t-tests. The results showed that sex was significantly associated with myocardial infarction type (p=0.018), while NSTEMI patients were significantly older than STEMI patients (p=0.014). The median platelet count was significantly higher in STEMI patients than in NSTEMI patients (416,500 vs. 310,000 cells/mm³; p<0.001). Mean MPV, PDW, and PCT values were also significantly higher in STEMI patients, with p-values of 0.015, 0.001, and 0.007, respectively. In conclusion, platelet count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), and Plateletcrit (PCT) differed significantly between STEMI and NSTEMI patients and may serve as additional hematological parameters in the evaluation of ACS patients.
No takes yet. Share an insight, caveat, or question.
Budi et al. (2026) conducted an observational in Acute Coronary Syndrome (STEMI and NSTEMI) (n=104). ST-Elevation Myocardial Infarction (STEMI) vs. Non-ST-Elevation Myocardial Infarction (NSTEMI) was evaluated on Platelet indices (median platelet count, mean platelet volume [MPV], platelet distribution width [PDW], and plateletcrit [PCT]) (p=<0.001). STEMI patients had significantly higher median platelet counts (416,500 vs. 310,000 cells/mm³; p<0.001) as well as higher MPV (p=0.015), PDW (p=0.001), and PCT (p=0.007) than NSTEMI patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: