Perioperative NT pro BNP can predict severe postoperative complications in elderly patients undergoing noncardiac surgery

Figures

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  Fig. 1. The diagram of flow chart.

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  Fig. 2. The result of DCA between Pre-model and Post-model. The sloping thin grey line is the net benefit of treating all men whether or not undergoing postoperative severe complication; the green line is the net benefit of treating men on the predicting of the Pre-model; the red line is the net benefit of treating men on the predicting of Post-model; the horizontal thick black line is the net benefit of treating no man. The DCA demonstrated that the Pre-model achieved higher clinical net benefit under the decision threshold probability lower than 0.3 compared to Post-model. In contrast, Post-model had a higher clinical net benefit when the decision threshold probability was greater than 0.3. DCA: decision curve analysis; NT-Pro BNP: N-terminal pro-B-type natriuretic peptide; Pre-model: the model based on preoperative NT-Pro BNP; Post-model: the model based on postoperative NT-Pro BNP.

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  Fig. 3. Nomogram (A) and ROC (B) of Pre-model and the web calculator (C). A: Through drawing a vertical line from corresponding variable to the top line (Points), the score of every variable and total score can be got. The predicted probability can be obtain by drawing a vertical line form the total points line to the bottom risk line. C In the web calculator developed by us, directly input the value of the corresponding variable on the left side, the result of prediction probability and 95% confidence interval will be output on the right side. ROC: receiver operating characteristic curve; ASA-PS: American Society of Anesthesiologists Physical Status; NT-Pro BNP: N-terminal pro-B-type natriuretic peptide; Pre-model: the model based on preoperative NT-Pro BNP.

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  Fig. 4. Nomogram (A) and ROC (B) of Pre-model and the web calculator (C). A: Through drawing a vertical line from corresponding variable to the top line (Points line), the score of every variable and total score can be got. The predicted probability can be obtain by drawing a vertical line form the total points line to the bottom risk line. C: In the web calculator developed by us, directly input the value of the corresponding variable on the left side, the result of prediction probability and 95% confidence interval will be output on the right side. ROC: receiver operating characteristic curve; ASA-PS: American Society of Anesthesiologists Physical Status; NT-Pro BNP: N-terminal pro-B-type natriuretic peptide; Post-model: the model based on postoperative NT-Pro BNP.