Key result
Carotid artery stenting has shown equivalency or superiority to endarterectomy in high-risk patients, but randomized trials in non-high-risk patients are still lacking.
Why the study?
Is carotid artery stenting equivalent or superior to carotid artery endarterectomy in patients with carotid artery disease?
Is carotid artery stenting equivalent or superior to carotid artery endarterectomy in patients with carotid artery disease?
This review provides an overview of completed and ongoing trials comparing carotid artery stenting to endarterectomy, highlighting the need for randomized trials in non-high-risk patients.
Supports CAS in high-risk patients; leaves open equivalence to endarterectomy in lower-risk groups pending RCTs.
Carotid artery stenting (CAS) is growing as an alternative to carotid artery endarterectomy. Nowadays, it is performed routinely in many centers worldwide. Still, it is discussed controversially although several clinical trials have shown equivalency or superiority of catheter treatment at least in high-risk patients. What is still missing is a randomized trial in non-high-risk patients. This is an overview about the completed and ongoing trials as well as the current stent and embolic protection technology.
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Rabe et al. (2004) conducted a review in Carotid artery disease. Carotid artery stenting vs. Carotid artery endarterectomy was evaluated. Carotid artery stenting has shown equivalency or superiority to endarterectomy in high-risk patients, but randomized trials in non-high-risk patients are still lacking.
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