Key result
Inadvertent administration of a supratherapeutic dose of norepinephrine during PCI induced Takotsubo cardiomyopathy and cardiogenic shock, which fully resolved within one week with intra-aortic balloon pump support.
Case Report (n=1)
No
Iatrogenic Takotsubo cardiomyopathy should be considered when a patient presents with ACS-like symptoms and cardiogenic shock following exogenous catecholamine administration during PCI.
Vigilance for catecholamine-triggered TTC is prudent during PCI; this case leaves open incidence, risk factors, and prevention strategies.
Takotsubo cardiomyopathy (TTC) is characterized by reversible ventricular dysfunction induced by endogenous and, occasionally, exogenous catecholamine. We present a report on a patient who developed TTC and cardiogenic shock during percutaneous coronary intervention (PCI) secondary to inadvertent norepinephrine administration. His hemodynamic status and cardiac function were totally restored within 1 week after hemodynamic support using intra-aortic balloon pump without sequela. Thus, TTC should be considered once a patient presents with symptoms mimicking acute coronary syndrome (ACS) after catecholamine administration.
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Chen et al. (2020) conducted a case report in Takotsubo cardiomyopathy (n=1). Norepinephrine overdose was evaluated on Clinical recovery from cardiogenic shock and Takotsubo cardiomyopathy. Inadvertent administration of a supratherapeutic dose of norepinephrine during PCI induced Takotsubo cardiomyopathy and cardiogenic shock, which fully resolved within one week with intra-aortic balloon pump support.
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