What does this research mean for the field?

On-body wearable injectors are uniquely positioned to address the growing demand for large-volume subcutaneous delivery of biologic therapies by bridging usability, volume capability, and at-home administration. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the device landscape, clinical utility, and strategic development requirements for on-body wearable injectors delivering large-volume, high-viscosity biologic therapies.

September 8, 2026Expert Opinion on Drug Delivery

Addressing the needs for large-volume subcutaneous drug delivery: the case for on-body wearable injectors

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Authors

RPRonald J. PettisBecton Dickinson (United States)

Discussion

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Implication

Critical review demonstrates advantages of wearable on-body injectors for large-volume biologic administration, highlighting improved feasibility of at-home patient self-care.

Key Points

To evaluate the device landscape, clinical utility, and strategic development requirements for on-body wearable injectors delivering large-volume, high-viscosity biologic therapies.
Conducted a critical perspective surveying commercial and in-development subcutaneous delivery systems.
Evaluated device performance trade-offs regarding volume capacity, viscosity management, user convenience, and at-home versus clinical administration.
On-body injectors address critical delivery barriers by supporting larger fluid volumes and higher viscosities that standard autoinjectors cannot accommodate.
Subcutaneous transition reduces clinic chair time and treatment costs for healthcare providers while minimizing lifestyle disruptions for patients.

Cite This Study

Ronald J. Pettis (2026) studied this question.

synapsesocial.com/papers/6a9fd74958e84d0ff5b45c0e https://doi.org/10.1080/17425247.2026.2725755

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Implication

Critical review demonstrates advantages of wearable on-body injectors for large-volume biologic administration, highlighting improved feasibility of at-home patient self-care.

Addressing the needs for large-volume subcutaneous drug delivery: the case for on-body wearable injectors

Discussion

Member takes

Implication

Key Points

Cite This Study

Addressing the needs for large-volume subcutaneous drug delivery: the case for on-body wearable injectors

Discussion

Member takes

Implication

Key Points

Cite This Study

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