Development of the Japanese version of the Manchester short assessment of quality of life (MANSA) among people with self-reported severe mental illness
Cross-sectional survey reveals acceptable validity and reliability for a quality-of-life assessment in severe mental illness, highlighting its utility for psychiatric care.
Key Points
To develop a Japanese version of the Manchester Short Assessment of Quality of Life (MANSA) and evaluate domain-specific associations with psychiatric diagnoses among adults with severe mental illness.
Translated the 12-item MANSA instrument into Japanese and administered it in a cross-sectional survey of 237 adults with self-reported severe mental illness in Japan.
Assessed concurrent validity among 38 participants who concurrently completed the WHOQOL26 instrument.
Split the cohort randomly to conduct exploratory factor analysis (EFA) and confirmatory factor analysis (CFA), while evaluating internal consistency and domain-level ordinal logistic regressions.
The 12-item instrument demonstrated good internal consistency with a Cronbach's alpha of 0.877, though CFA fit indices for a two-factor structure were inadequate (CFI = 0.86, TLI = 0.82, RMSEA = 0.12).
All item factor loadings exceeded 0.40 under a one-factor EFA model, supporting the practical use of an overall mean score.
Participants with schizophrenia-spectrum conditions reported higher scores in several domains than those with bipolar or depressive disorders, and symptom stability positively associated with scores across all domains.