Screening of chloramphenicol residues in chickens and fish in Chittagong city of Bangladesh

Chloramphenicol, an illegal antibiotic has been widely used in aquaculture and poultry as an anti-microbial agent which has been banned in many countries for its toxic side effects. A random screening of chloramphenicol residues in some poultry and fishes by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) have been carried out. The determined concentrations of chloramphenicol in farmed and wild chickens and its liver, various types of farmed fishes were in the range of minimum value of 0.133 µg/ kg to the highest value of 0.515 µg/ kg. The lowest concentration of 0.133 µg/ kg was determined in Pungas fish and the highest of 0.515 µg/ kg in Rui fish. Minimum Required Performance Limit (MRPL) in food of animal origin like Meat, Eggs, Milk, Urine, Honey and Aquaculture products for Chloramphenicol is 0.3 µg/ kg. The results of eight samples out of thirteen have been exceeded the limit of MRPL. So it is a matter of great concern for us.DOI: http://dx.doi.org/10.3329/bjvm.v11i2.19144Bangl. J. Vet. Med. (2013).11(2): 173-175