Key result
ACE inhibitors reduce mortality and morbidity in post-MI patients, while verapamil and diltiazem are beneficial except in those with heart failure without reversible ischemia.
Why the study?
Do ACE inhibitors and calcium antagonists reduce mortality and morbidity in patients after an acute myocardial infarction?
Population
Patients after an acute myocardial infarction
Design
Review
Authors
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May support ACE inhibitor preference post-MI; leaves open calcium antagonist role in HF subgroups.
Do ACE inhibitors and calcium antagonists reduce mortality and morbidity in patients after an acute myocardial infarction?
ACE inhibitors and non-dihydropyridine calcium antagonists (verapamil, diltiazem) improve outcomes post-myocardial infarction, whereas nifedipine may be harmful.
Stig Persson (1995) conducted a review in Acute myocardial infarction. Angiotensin converting enzyme (ACE) inhibitors and calcium antagonists was evaluated on Mortality and morbidity. ACE inhibitors reduce mortality and morbidity in post-MI patients, while verapamil and diltiazem are beneficial except in those with heart failure without reversible ischemia.
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