Key result
Preoperative IV dexamethasone significantly reduced the overall incidence of postoperative vomiting compared to saline (23% vs 51%) in children undergoing adenotonsillectomy.
Why the study?
Does preoperative IV dexamethasone reduce postoperative vomiting in children undergoing electrodissection adenotonsillectomy?
Population
110 children 2–12 years old undergoing electrodissection adenotonsillectomy
Comparison
Dexamethasone 0.5 mg/kg IV administered… vs Saline (placebo)
Design
RCT, Randomized, Double-blinded, placebo-controlled
Follow-up
Postoperative period
Authors
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Supports routine preoperative IV dexamethasone to reduce vomiting after pediatric adenotonsillectomy; confirms antiemetic efficacy in this population.
RCT (n=110)
double-blinded
randomized
Does preoperative IV dexamethasone reduce postoperative vomiting in children undergoing electrodissection adenotonsillectomy?
Absolute Event Rate: 23% vs 51%
Preoperative IV dexamethasone significantly reduces postoperative vomiting and improves oral intake in children undergoing adenotonsillectomy.
Aouad et al. (2001) conducted an RCT in Postoperative vomiting after tonsillectomy (n=110). Dexamethasone vs. Saline was evaluated on Overall incidence of vomiting. Preoperative IV dexamethasone significantly reduced the overall incidence of postoperative vomiting compared to saline (23% vs 51%) in children undergoing adenotonsillectomy.
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