Key result
A time to peak (TTP) of less than 127 ms on tissue Doppler imaging predicted pulmonary hypertension with an area under the curve of 0.746 compared to right heart catheterization.
Why the study?
Does the TDI parameter TTP accurately predict pulmonary hypertension in patients referred for right heart catheterization?
Cross-Sectional (n=60)
No
Does the TDI parameter TTP accurately predict pulmonary hypertension in patients referred for right heart catheterization?
Effect estimate: AUC 0.746
p-value: p=<0.001
The novel TDI parameter TTP (<127 ms) offers an acceptable non-invasive method to estimate pulmonary hypertension with moderate sensitivity and specificity.
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Supports noninvasive TTP for PH estimation; leaves open clinical adoption pending prospective validation.
Ghaderi et al. (2016) conducted a cross-sectional in Suspected pulmonary hypertension (n=60). Time to peak (TTP) measured by tissue Doppler imaging vs. Right heart catheterization (RHC) was evaluated on Diagnosis of pulmonary hypertension (mean PAP ≥ 25 mmHg) (AUC 0.746, p=<0.001). A time to peak (TTP) of less than 127 ms on tissue Doppler imaging predicted pulmonary hypertension with an area under the curve of 0.746 compared to right heart catheterization.
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