This study describes the facile, controllable production of nano-hydroxyapatite (HA), with sheet, rod, or tube morphology, using a continuous-flow hydrothermal reactor. We also demonstrate the synthesis of parascholzite, a mineral rarely described, using the same reactor. Cell viability assays show that HA generated in our reactor have no cytotoxic effects on mouse embryonic stem cells (mESC).
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Lester et al. (2013) studied this question.
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