Key result
The antipsychotic drug flupenthixol induced self-terminating torsades de pointes in a permanently paced patient at a slow heart rate following a single episode of loose stool.
Demonstrates that multiple factors including Flupenthixol, slow paced heart rate, and mild illness can precipitate torsades de pointes.
Case signals multifactorial torsades risk with Flupenthixol in paced patients during illness; leaves open systematic risk evaluation.
Torsades de pointes is ventricular tachycardia due to prolongation of the heart rate-corrected QT interval (QTc). It is caused by multiple factors. Here we present a case of self terminating torsades de pointes due to antipsychotic drug Flupenthixol in a permanently paced patient at slow heart rate who developed torsades de pointes only after one episode of loose stool .
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Dwivedi et al. (2015) studied this question. The antipsychotic drug flupenthixol induced self-terminating torsades de pointes in a permanently paced patient at a slow heart rate following a single episode of loose stool.
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