Key result
A non-dipping blood pressure pattern in women with gestational hypertension was associated with a significantly higher rate of preterm delivery compared to a dipping pattern (43.3% vs 13.3%; p=0.01).
Why the study?
To determine whether the non-dipping pattern of blood pressure influences preterm delivery, maternal clinical findings, and birth weight in gestational hypertension.
Does a non-dipping blood pressure pattern increase the risk of preterm delivery and affect birth weight in women with gestational hypertension?
Observational (n=60)
Does a non-dipping blood pressure pattern increase the risk of preterm delivery and affect birth weight in women with gestational hypertension?
Absolute Event Rate: 43.3% vs 13.3%
p-value: p=0.01
A non-dipping blood pressure pattern in gestational hypertension is associated with a higher risk of preterm delivery, lower birth weight, and altered maternal echocardiographic findings.
Non-dipping BP in GH was associated with preterm delivery; leaves open whether ABPM monitoring improves outcomes in prospective studies.
The study aimed to determine if the non-dipping pattern of blood pressure (BP) influences preterm delivery in gestational hypertension (GH), but also maternal clinical findings and birth weight. Sixty women with GH, i.e. 30 women with a dipping BP profile (control group) and 30 non-dippers (study group), were included in the study. Echocardiography was performed in all subjects, as well as ambulatory blood pressure monitoring (ABPM) during third trimester. ABPM was repeated 6-8 weeks after delivery. Thirteen women with preterm delivery were classified as non-dippers and only four as dippers (p=0.01). The average and peak systolic and diastolic night-time BP had negative linear correlation with birth weight (p<0.0005). Total vascular resistance (p<0.0005) and mass index (p=0.014) were significantly higher as compared with women with term delivery, while ejection fraction (EF) (p=0.007) and circumferential systolic velocity (p=0.042) were significantly reduced in the preterm delivery group. Multivariate binary logistic regression identified the average night-time systolic BP, left ventricular mass index and EF as independent predictors of preterm delivery. Study results suggested a relationship of the non-dipping BP pattern in GH with preterm delivery, birth weight, and maternal clinical findings.
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Đorđe Ilić (2021) conducted an observational in Gestational hypertension (n=60). Non-dipping blood pressure pattern vs. Dipping blood pressure pattern was evaluated on Preterm delivery (p=0.01). A non-dipping blood pressure pattern in women with gestational hypertension was associated with a significantly higher rate of preterm delivery compared to a dipping pattern (43.3% vs 13.3%; p=0.01).
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