Key result
Consumption of 250 ml of regular or dealcoholized red wine prevented the acute decrease in flow-mediated dilatation (P<0.001) induced by smoking one cigarette in healthy smokers.
Why the study?
Does red wine or dealcoholized red wine prevent acute endothelial dysfunction induced by smoking in healthy smokers?
RCT (n=20)
Double-blind
Does red wine or dealcoholized red wine prevent acute endothelial dysfunction induced by smoking in healthy smokers?
p-value: p=<0.001
Red wine and dealcoholized red wine counteract the acute endothelial dysfunction caused by smoking one cigarette in healthy smokers, likely due to antioxidant constituents.
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Acute red wine intake may blunt smoking-induced endothelial dysfunction; extends RCT evidence for polyphenol effects independent of alcohol.
Karatzi et al. (2007) conducted an RCT in Healthy smokers (n=20). Red wine or dealcoholized red wine vs. Smoking one cigarette without wine was evaluated on Flow mediated dilatation (FMD) (p=<0.001). Consumption of 250 ml of regular or dealcoholized red wine prevented the acute decrease in flow-mediated dilatation (P<0.001) induced by smoking one cigarette in healthy smokers.
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