Key result
Platelet counts did not differ significantly between pulmonary arterial blood and radial arterial blood (192.132 vs. 192.004 x 10^9/l), failing to support the theory of pulmonary platelet production.
Why the study?
Are there differences in platelet parameters between blood entering and leaving the lungs in patients undergoing aorto-coronary bypass?
Population
151 patients undergoing aorto-coronary bypass
Comparison
Blood sampling from the pulmonary artery vs Blood sampling from the radial artery or aorta
Design
Cross-sectional
Authors
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No platelet difference across lungs in CABG; leaves open pulmonary thrombopoiesis hypothesis pending prospective data.
Cross-Sectional (n=151)
Are there differences in platelet parameters between blood entering and leaving the lungs in patients undergoing aorto-coronary bypass?
Absolute Event Rate: 192.132% vs 192.004%
This study found no difference in platelet parameters between blood entering and leaving the lungs, challenging the theory that significant thrombopoiesis occurs in the lungs.
Aliberti et al. (2002) conducted a cross-sectional in Patients undergoing aorto-coronary bypass (n=151). Pulmonary arterial blood sampling vs. Radial arterial or aortic blood sampling was evaluated on Platelet count (x 10^9/l). Platelet counts did not differ significantly between pulmonary arterial blood and radial arterial blood (192.132 vs. 192.004 x 10^9/l), failing to support the theory of pulmonary platelet production.
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