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October 26, 2025Archives of VirologyOpen Access

Detection of the intergenic region III and multigene family 505 9R and 10R-V variant of African swine fever virus genotype II on pig farms in South Korea

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Population

African swine fever samples collected from eight pig farms between July 2023 and July 2024

Design

Genetic analysis study

Key result

Genetic analysis of eight ASFV isolates from South Korean pig farms revealed the emergence of novel multigene family 505_9R/10R-V variations in four isolates and an intergenic region III variant in one isolate.

Authors

KCKi-Hyun ChoDKDa‐Young KimSHSeong‐Keun Hong

Discussion

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Overview

Alerts to emerging ASFV variants in Korean swine; leaves open needs for expanded surveillance and vaccine matching.

Study Design

Type

Observational (n=8)

Structured PICO

P
Population
8 African swine fever virus isolates collected from pig farms in South Korea between July 2023 and July 2024 subjected to genetic analysis.
E
Exposure
Genetic analysis
O
Outcome
Genetic variation and evolution of ASFV isolates

The study identifies novel genetic variants of the African swine fever virus circulating in South Korean pig farms, emphasizing the need for enhanced genetic surveillance.

Limitations

  • Lack of related reference sequences from wild boars greatly limits the ability to carry out molecular epidemiology studies.
  • Virulence of these strains needs to be assessed through challenge experiments.

Cite This Study

Cho et al. (2025) conducted an observational in African swine fever (n=8). African swine fever virus variants was evaluated on Genetic characterization of ASFV isolates. Genetic analysis of eight ASFV isolates from South Korean pig farms revealed the emergence of novel multigene family 505_9R/10R-V variations in four isolates and an intergenic region III variant in one isolate.

synapsesocial.com/papers/6aa01d6086888c826790e14chttps://doi.org/10.1007/s00705-025-06450-y
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